HarmoniaMentis Sverige
Angel Aledo-Serrano: Impact of delayed treatment or medication switch in Epilepsy
"Time is brain" – learn how early seizure control, timely surgery, and treatment strategies impact morbidity, mortality, and long-term outcomes in epilepsy.
Introduction
In his talk dr. Aledo-Serrano shared the concept of “time is brain” when discussing about increased risk of morbidity and mortality with epilepsy and how treatment practices are reflected in real-world studies. The duration of epilepsy before epilepsy surgery predicts surgery outcome1 whereas baseline ASM polytherapy is associated with a reduced risk of early death2. Evidence indicates that earlier and effective seizure control is considered essential for optimal outcomes.
Dr. Angel Aledo-Serrano (MD, PhD) is director of the Vithas Clinical Neuroscience Institute at Vithas University Hospitals, Madrid, Spain
- Radhakrishnan A, Menon R, Thomas SV et al. “Time is Brain”—How early should surgery be done in drug-resistant TLE? Acta Neur Scan. 2018;138(6):531-40
- Hrabok M, Engbers JDT, Wiebe S et al. Primary care electronic medical records can be used to predict risk and identify potentially modifiable factors for early and late death in adult onset epilepsy. 2021;62:51-60